N-去甲基伊马替尼 N-Desmethyl Imatinib 404844-02-6
N-去甲基伊马替尼
甲磺酸伊马替尼杂质H;伊马替尼EP杂质C(N-去甲基伊马替尼);伊马替尼N-脱甲基杂质;去甲基伊马替尼(杂质);伊马替尼杂质C(EP);伊马替尼EP杂质C;N-去甲基伊马替尼(杂质);去甲基伊马替尼D8
N-Desmethyl Imatinib
CGP-74588;N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-benzamide;Norimatinib;STI509-00;Imatinibimpurity6/ImatinibEPImpurityC/N-DesmethylImatinib/N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(piperazin-1-ylmethyl)benzamide;Benzamide,N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-;IMATINIBMETABOLITEN-DESMETHYLIMATINIB(N-DESMETHYLIMATINIB);N-{4-Methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}-4-(piperazin-1-ylmethyl)benzamide
404844-02-6
C28H29N7O
479.58
1.268±0.06 g/cm3(Predicted)
99-101°C
DMF：16mg/mL； DMF:PBS (pH 7.2) (1:4)：0.20 mg/ml； DMSO：14mg/mL；乙醇：0.20mg/mL
-20°C Freezer
用途 N-去甲基伊马替尼为杂环衍生物，可用作医药中间体。
生物活性 N-Desmethylimatinib(Norimatinib)是Imatinib(HY-15463)的代谢物。Imatinib是一个靶向v-Abl、c-Kit和PDGFR多靶点抑制剂。
